Ademtech magnetic nanoparticles (200nm, 300nm, 500nm) offer large surface area for binding and eliminate the sedimentation problems that affect larger particles. Adembeads present a smooth surface exhibiting a low non–specific binding on the opposite of other available rough particles. Thanks to the high iron content (> 70%) the rapid separation under magnetic field is not compromised. To ensure reliability of your assay, the tightly controlled production processes provide with a calibrated (CV<20%) spherical nanoparticles with highly reproducible characteristics.
CHOOSE THE IDEAL MAGNETIC NANOPARTICLES TO YOUR APPLICATION
LARGE CHOICE OF SIZE
o 200nm and 300nm respectively provide with a 15 m2/g and 10 m2/g
o MasterBeads, 500nm provide with a 5 m2/g surface. MasterBeads have an improved magnetic response and keep all benefits of Adembeads (no sedimenation) and are particularly suitable for automation. See the Masterbeads Streptavidin.
LARGE CHOICE OF BINDING CAPACITIES = 5 levels of biotin-binding capacities are now available to choose the capacity needed to optimize your application.o Streptavidin: natural streptavidin from S. avidinii
LARGE CHOICE OF SURFACE = Adembeads are available pre-coated with
o Streptavidin plus: natural streptavidin from S. Avidinii with improved binding capacities
o StreptaDivin: neutralized avidin from eggs without carbohydrates and tripeptide sequence Arg–Tyr–Asp (RYD).
The StreptaDivin has a isolectric point of 6.3. These features provide very low non-specific binding.
o rec-Streptavidin: recombinant streptavidin from E. Coli
also available in 500nm ! see HERE
9 differents streptavidin particles !
Streptavidin particles are suplied in Storage Buffer (#10201) at 0,5% (5mg/ml)
Immobilisation Buffer (#10301) can be used for biotinylated ligand capture.
References:1 Sensors & Actuators: B. Chemical, 134 (2), p.755-760, Sep 2008, An impedimetric DNA sensor based on functionalizd magnetic nnoparticles for HIV and HBV detection Hassen, W.M. / Chaix, C. / Abdelghani, A. / Bessueille, F. / Leonard, D. / Jaffrezic-Renault, N.
2-Electrochemistry Communications, 10 (8), p.1152-1154, Aug 2008, A conductometric immunosensor based on functionalized magnetite nanoparticles for E. coli detection Hnaiein, M. / Hassen, W.M. / Abdelghani, A. / Fournier-Wirth, C. / Coste, J. / Bessueille, F. / Leonard, D. / Jaffrezic-Renault, N.
3-Materials Science & Engineering C, 28 (5), p.820-825, Jul 2008, Under flow impedimetric measurements using magnetic particles for label-free detection affinity target, Hassen, W.M. / Angnes, L. / Abdelghani, A. / Bessueille, F. / Leonard, D. / Jaffrezic-Renault, N.
4-Immunology Letters Volume 125, Issue 2 15 August 2009, Pages 100-104 Exogenous HIV-1 Vpr disrupts IFN-α response by plasmacytoid dendritic cells (pDCs) and subsequent pDC/NK interplay Henoch Sangjoon Hong, Nupur Bhatnagar, Matthias Ballmaier, Ulrich Schubert, Peter Henklein, Thorsten Volgmann, Hans eiken, Reinhold E. Schmidt and Dirk Meyer-Olson
5- BioTechniques 46:543-549 (June 2009) doi 10.2144/000113124 Simple non-fluorescent polarity labeling of microtubules for molecular motor assays Virupakshi Soppina, Arpan K. Rai, and Roop Mallik
6-Biosensors and Bioelectronics, 24 (7), p.1893-1898, Mar 2009, Rapid DNA multi-analyte immunoassay on a magneto-resistance biosensor Koets, M. / van der Wijk, T. / van Eemeren, J.T.W.M. / van Amerongen, A. / Prins, M.W.J