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1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) is a water-soluble derivative of carbodiimide. Carbodiimide catalyzes the formation of amide bonds between carboxylic acids or phosphates and amines by activating carboxyl or phosphate to form an O-urea derivative. This derivative reacts readily with nucleophiles (see figure below). The reagent can be used to peptide bonds from acid and amines.

  • simple use with the protocol provided
  • convenient for covalent linkage of proteins on Carboxyl-Adembeads (200 or 300nm) and MasterBeads Carboxylic Acid (500nm)


EDC reacts with a carboxyl group first and forms an amine reactive intermediate which is unstable in solution.
Quantity available:
-    15mg / 10401
-    50mg / 10402
-  100mg / 10403
-  200mg / 10404

 Activation Buffer
 Storage Buffer
 MasterBeads Carboxylic Acid
 Guide:Coating Reagents.pdf
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